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Review
. 1986:37:215-24.
doi: 10.1146/annurev.me.37.020186.001243.

Action and toxicity of cyclosporine

W M Bennett, D J Norman
Review

Action and toxicity of cyclosporine

W M Bennett et al. Annu Rev Med. 1986.

Abstract

Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.

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