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Randomized Controlled Trial
. 2018 Apr;93(4):182-185.
doi: 10.1016/j.oftal.2017.12.015. Epub 2018 Feb 15.

Superdiluted atropine at 0.01% reduces progression in children and adolescents. A 5 year study of safety and effectiveness

[Article in English, Spanish]
M Diaz-Llopis  1 , M D Pinazo-Durán  2
Affiliations
Randomized Controlled Trial

Superdiluted atropine at 0.01% reduces progression in children and adolescents. A 5 year study of safety and effectiveness

[Article in English, Spanish]
M Diaz-Llopis et al. Arch Soc Esp Oftalmol (Engl Ed). 2018 Apr.

Abstract

Objective: To confirm the clinical security and effectiveness of the daily application of 0.01% superdiluted atropine eyedrops in the progression of myopia in children.

Material and methods: A total of 200 children 9-12 years of age were randomised into a treated group and a control without treatment. Refraction under cycloplegia was performed.

Results: Myopia progression of the treated group was -0.14±0.35 versus -0.65±0.54 in the control group without treatment. Only 2% of patients were forced to stop treatment due to side effects.

Conclusion: Atropine superdiluted atropine 0.01% eyedrops is effective and well tolerated, and reduced myopia progression by 25%.

Keywords: 0,01%; 0.01%; Children; Frenar; Miopía; Myopia; Niños; Progresión; Progression; Slow-down.

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