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. 2017 Oct;17(4):786-802.

Reconstructing time-to-event data from published Kaplan-Meier curves

Yinghui Wei  1 , Patrick Royston  2
Affiliations

Reconstructing time-to-event data from published Kaplan-Meier curves

Yinghui Wei et al. Stata J. 2017 Oct.

Abstract

Hazard ratios can be approximated by data extracted from published Kaplan-Meier curves. Recently, this curve approach has been extended beyond hazard-ratio approximation with the capability of constructing time-to-event data at the individual level. In this article, we introduce a command, ipdfc, to implement the reconstruction method to convert Kaplan-Meier curves to time-to-event data. We give examples to illustrate how to use the command.

Keywords: Kaplan–Meier curves; hazard ratios; ipdfc; st0498; time-to-event data.

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Figures

Figure 1
Figure 1
Reconstructed Kaplan–Meier curves for locoregional control among patients with head and neck cancer (Bonner et al. 2006). Patients are randomized to receive radiotherapy plus cetuximab or radiotherapy alone.
Figure 2
Figure 2
Reconstructed Kaplan–Meier curves for progression-free survival according to treatment group in icon7 (Perren et al. 2011). Patients are randomized to receive standard chemotherapy plus bevacizumab or standard chemotherapy alone.
Figure 3
Figure 3
Reconstructed Kaplan–Meier curves for time to first occurrence of event. Patients are randomly assigned to perindopril treatment or placebo in the europa trial (Fox 2003).
See this image and copyright information in PMC

References

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