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Review
. 2017 Dec;7(4):515-530.
doi: 10.15171/apb.2017.064. Epub 2017 Dec 31.

Cross-Linked Hydrogel for Pharmaceutical Applications: A Review

Rabinarayan Parhi  1
Affiliations
Review

Cross-Linked Hydrogel for Pharmaceutical Applications: A Review

Rabinarayan Parhi. Adv Pharm Bull. 2017 Dec.

Abstract

Hydrogels are promising biomaterials because of their important qualities such as biocompatibility, biodegradability, hydrophilicity and non-toxicity. These qualities make hydrogels suitable for application in medical and pharmaceutical field. Recently, a tremendous growth of hydrogel application is seen, especially as gel and patch form, in transdermal drug delivery. This review mainly focuses on the types of hydrogels based on cross-linking and; secondly to describe the possible synthesis methods to design hydrogels for different pharmaceutical applications. The synthesis and chemistry of these hydrogels are discussed using specific pharmaceutical examples. The structure and water content in a typical hydrogel have also been discussed.

Keywords: Cross-linking; Hydrogel; Polymers; Thermoreversible gel.

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