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Comment
. 2018 Jan 22;44(2):133-135.
doi: 10.1016/j.devcel.2018.01.001.

A Dual Binding Receptor for ER-phagy

Noboru Mizushima  1
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A Dual Binding Receptor for ER-phagy

Noboru Mizushima. Dev Cell. .
Free article

Abstract

Selective autophagy of the endoplasmic reticulum (ER)-ER-phagy-is mediated by multiple receptors. In this issue of Developmental Cell, Smith et al. (2018) identify ER membrane protein CCPG1 as an ER-phagy receptor that interacts with autophagy-related proteins GABARAPs and FIP200 and ensures ER protein homeostasis, especially in pancreatic acinar cells.

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