Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2018;24(1):1-8.
doi: 10.1159/000485564. Epub 2018 Jan 19.

Mentalization-Based Treatment for Concurrent Borderline Personality Disorder and Substance Use Disorder: A Randomized Controlled Feasibility Study

Affiliations
Randomized Controlled Trial

Mentalization-Based Treatment for Concurrent Borderline Personality Disorder and Substance Use Disorder: A Randomized Controlled Feasibility Study

Björn Philips et al. Eur Addict Res. 2018.

Abstract

Aims: There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use disorder (SUD). Mentalization-based treatment (MBT) have shown efficacy in several trials on BPD. The aim of the present study was to examine the feasibility and effectiveness of MBT for concurrent BPD and SUD.

Methods: Patients (n = 46) with concurrent BPD and SUD were randomized either to MBT in combination with SUD treatment (n = 24) or to SUD treatment alone (n = 22). Outcome was measured after 18 months using objective data, as well as interview and self-report measures.

Results: There was no significant difference between the groups on any outcome variable. No suicide attempts occurred in the MBT group in contrast to 4 suicide attempts that occurred in the control group - a difference that did not reach statistical significance (p = 0.06). A majority of the therapists did not show sufficient MBT adherence and quality.

Conclusion: MBT for patients with concurrent BPD and SD does not appear to be harmful; on the other hand, it is possibly helpful in reducing the risk involved in suicide attempts.

Keywords: Borderline personality disorder; Psychotherapy; Randomized controlled trial; Substance-related disorders.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
CONSORT flow diagram for Mentalization-Based Treatment for Dual Diagnosis (MBTDD) – a randomized controlled trial.

References

    1. Chesney E, Goodwin GM, Fazel S. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry. 2014;13:153–160. - PMC - PubMed
    1. Cheng AT, Chen TH, Chen CC, Jenkins R. Psychosocial and psychiatric risk factors for suicide. Case-control psychological autopsy study. Br J Psychiatry. 2000;177:360–365. - PubMed
    1. Youdelis-Flores C, Ries RK. Addiction and suicide: a review. Am J Addict. 2015;24:98–104. - PubMed
    1. Hjorthøj C, Østergaard ML, Benros ME, et al. Association between alcohol and substance use disorders and all-cause and cause-specific mortality in schizophrenia, bipolar disorder, and unipolar depression: a nationwide, prospective, register-based study. Lancet Psychiatry. 2015;2:801–808. - PubMed
    1. Steingrimsson S, Sigurdsson MI, Aspelund T, Sigfusson S, Magnusson A. Total population-based study of the impact of substance use disorders on the overall survival of psychiatric inpatients. Nord J Psychiatry. 2016;70:161–166. - PubMed

Publication types