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Randomized Controlled Trial
. 2018 Feb 6:24:743-750.
doi: 10.12659/msm.905636.

Effects of High-Frequency Repetitive Transcranial Magnetic Stimulation Combined with Task-Oriented Mirror Therapy Training on Hand Rehabilitation of Acute Stroke Patients

Jinhong Kim  1 , Jongeun Yim  1
Affiliations
Randomized Controlled Trial

Effects of High-Frequency Repetitive Transcranial Magnetic Stimulation Combined with Task-Oriented Mirror Therapy Training on Hand Rehabilitation of Acute Stroke Patients

Jinhong Kim et al. Med Sci Monit. .

Abstract

BACKGROUND Impairments of hand function make it difficult to perform daily life activities and to return to work. The aim of this study was to investigate the effect of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) combined with task-oriented mirror therapy (TOMT) on hand rehabilitation in acute stroke patients. MATERIAL AND METHODS Twenty subacute stroke patients in the initial stages (<3 months) participated in the study. Subjects were allocated to 2 groups: the experimental group received HF-rTMS + TOMT and the control group received HF-rTMS. TOMT training was conducted in 10 sessions over 2 weeks for 30 min. rTMS was applied at a 20 Hz frequency over the hand motor area in the cortex of the affected hemisphere for 15 min. Outcomes, including motor-evoked potential (MEP), pinch grip, hand grip, and box and block test, were measured before and after training. RESULTS Significant improvements in the MEP and hand function variables were observed in both groups (p<0.05). In particular, hand functions (pinch grip and box and block test) were significantly different between the 2 groups (p<0.05). CONCLUSIONS HF-rTMS combined with TOMT had a positive effect on hand function and can be used for the rehabilitation of precise hand movements in acute stroke patients.

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Figures

Figure 1
Figure 1
Flow diagram of the experimental procedure.
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References

    1. Naro A, Bramanti A, Leo A, et al. Effects of cerebellar transcranial alternating current stimulation on motor cortex excitability and motor function. Brain Struct Funct. 2017;222(6):2891–906. - PubMed
    1. Gueugneau N, Grosprêtre S, Stapley P, Lepers R. High-frequency neuromuscular electrical stimulation modulates interhemispheric inhibition in healthy humans. J Neurophysiol. 2017;117(1):467–75. - PMC - PubMed
    1. Park E, Kim MS, Chang WH, et al. Effects of bilateral repetitive transcranial magnetic stimulation on post-stroke dysphagia. Brain Stimul. 2017;10(1):75–82. - PubMed
    1. Bernhardt J, Godecke E, Johnson L, Langhorne P. Early rehabilitation after stroke. Curr Opin Neurol. 2017;30(1):48–54. - PubMed
    1. Higgins J, Koski L, Xie H. Combining rTMS and task-oriented training in the rehabilitation of the arm after stroke: A pilot randomized controlled trial. Stroke Res Treat. 2013;2013:539146. - PMC - PubMed

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