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Case Reports
. 2017 Oct-Dec;8(4):378-381.
doi: 10.4103/jcvjs.JCVJS_70_17.

Primary dorsal spine primitive neuroectodermal tumor in an adult patient: Case report and literature review

Satyashiva Munjal  1 , Amit Srivastava  1 , Shivya Tucker  2 , Neha Bakshi  3 , Sunita Bhalla  3 , V S Mehta  1
Affiliations
Case Reports

Primary dorsal spine primitive neuroectodermal tumor in an adult patient: Case report and literature review

Satyashiva Munjal et al. J Craniovertebr Junction Spine. 2017 Oct-Dec.

Abstract

Primary spinal primitive neuroectodermal tumor (psPNET) is a rare entity with few cases reported in literature. We report a case of a 50-year-old female who presented to us with paraplegia and was diagnosed with extradural dorsal spine psPNET. The diagnosis was not suspected at presentation or on radiology but was established on histopathological examination. It is important to distinguish it from central nervous system primitive neuroectodermal tumors and from other spinal tumors since it follows a different clinical course and therapeutic outcome.

Keywords: Adult; dorsal spine; extradural; primitive neuroectodermal tumor.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Magnetic resonance imaging of the cervicodorsal spine. (a) T1 axial showing isointense tumor (asterisk) pushing cord to left (b) T2 sagittal image showing hyperintense lesion causing cord compression. (c) Short tau inversion recovery coronal image showing tumor (arrow head) extending through the foramen, cord (asterisk) being pushed to left. (d) Tumor heterogeneously enhancing to contrast on sagittal and coronal images
Figure 2
Figure 2
(a) Sagittal image showing enlargement of the foramen and thinning of pedicle (arrows). (b) Computed tomography image showing thinned out right side pedicle (arrow)
Figure 3
Figure 3
(a) Monomorphic tumor cells with vesicular chromatin, small nucleoli, and brisk mitotic karyorrhectic activity (H and E, ×40). (b) Diffuse membranous positivity for CD99 (×40). (c) Positivity for neuron-specific enolase (×20)
See this image and copyright information in PMC

References

    1. Saeedinia S, Nouri M, Alimohammadi M, Moradi H, Amirjamshidi A. Primary spinal extradural Ewing's sarcoma (primitive neuroectodermal tumor): Report of a case and meta-analysis of the reported cases in the literature. Surg Neurol Int. 2012;3:55. - PMC - PubMed
    1. Sharma BS, Khosla VK, Banerjee AK. Primary spinal epidural Ewing's sarcoma. Clin Neurol Neurosurg. 1986;88:299–302. - PubMed
    1. Ghanta RK, Koti K, Ghanta VS, Teegala R. Intracranial metastasis from primary spinal primitive neuroectodermal tumor. Asian J Neurosurg. 2013;8:42–7. - PMC - PubMed
    1. Ellis JA, Rothrock RJ, Moise G, McCormick PC, 2nd, Tanji K, Canoll P, et al. Primitive neuroectodermal tumors of the spine: A comprehensive review with illustrative clinical cases. Neurosurg Focus. 2011;30:E1. - PubMed
    1. Kepes JJ, Belton K, Roessmann U, Ketcherside WJ. Primitive neuroectodermal tumors of the cauda equina in adults with no detectable primary intracranial neoplasm – Three case studies. Clin Neuropathol. 1985;4:1–11. - PubMed

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