Updates in Chronic Obstructive Pulmonary Disease for the Year 2014
- PMID: 29404083
- PMCID: PMC5783065
- DOI: 10.5152/ttd.2015.4555
Updates in Chronic Obstructive Pulmonary Disease for the Year 2014
Erratum in
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Erratum.Turk Thorac J. 2015 Jul;16(3):140. Epub 2015 Jul 1. Turk Thorac J. 2015. PMID: 29404092 Free PMC article.
Abstract
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality in the world. Research conducted over the past decade has contributed much to our current knowledge of the pathogenesis and treatment of COPD. Additionally, an evolving literature has recently accumulated information about the management of COPD and also about exacerbations. This article reviews a concise summary on the updates in COPD including 1) new pathogenic mechanisms and therapeutic targets, 2) management of patients in Group B, C and D according to GOLD 2014 report; 3) prevention and management of exacerbation; 4) monitoring of natural history; and 5) essential but usually forgotten parts of the management.
Keywords: COPD; disease management; exacerbation; natural history.
Conflict of interest statement
Conflict of Interest: No conflict of interest was declared by the authors.
References
-
- Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Immunol Rev. 2008;8:183–92. http://dx.doi.org/10.1038/nri2254. - DOI - PubMed
-
- Barnes PJ. Mediators of chronic obstructive pulmonary disease. Pharm Rev. 2004;56:515–48. http://dx.doi.org/10.1124/pr.56.4.2. - DOI - PubMed
-
- Di Stefano A, Caramori G, Gnemmi I, et al. Th17-related cytokine expression is increased in the bronchial mucosa of stable COPD patients. Clin Exp Immunol. 2009;157:316–24. http://dx.doi.org/10.1111/j.1365-2249.2009.03965.x. - DOI - PMC - PubMed
-
- Barnes PJ. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2013;131:636–45. http://dx.doi.org/10.1016/j.jaci.2012.12.1564. - DOI - PubMed
-
- To Y, Ito K, Kizawa Y, et al. Targeting phosphoinositide-3-kinase-d with theophylline reverses corticosteroid insensitivity in COPD. Am J Resp Crit Care Med. 2010;182:897–904. http://dx.doi.org/10.1164/rccm.200906-0937OC. - DOI - PMC - PubMed
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