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. 2017 Apr;18(2):54-56.
doi: 10.5152/TurkThoracJ.2017.16039. Epub 2017 Mar 1.

Primary Pulmonary Malignant Fibrous Histiocytoma

Tuğba Coşgun  1 , Yelda Tezel  2 , Mustafa Akyıl  3 , İlker Kolbaş  3 , Ayçım Şen  4 , Çağatay Tezel  3
Affiliations

Primary Pulmonary Malignant Fibrous Histiocytoma

Tuğba Coşgun et al. Turk Thorac J. 2017 Apr.

Abstract

Malignant fibrous histiocytoma (MFH) cases are classified within the group of nonclassified sarcomas. The etiopathogenesis is unclear; however, MFH commonly develops in scar tissue and in areas exposed to radiation. MFH is the most common soft tissue sarcoma in adults and may be borne in the lungs, chest wall, mediastinum, or other tissues. Primary MFH of the lung constitutes less than 0.2% of all pulmonary neoplasms; thus, an optimal treatment strategy has not yet been elucidated. We aimed to report a case of MFH of the lung with subsequent treatment administration.

Keywords: Malignant fibrous histiocytoma; lung; pulmonary neoplasm.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1. a, b
Figure 1. a, b
A chest computed tomography (CT) scan revealed a 75×68×96 mm mass in the left lung. (a) Suspicion of tumor invasion to the first rib. (b) Adjacency of the tumor to mediastinal vascular structures
Figure 2. a, b
Figure 2. a, b
Positron emission tomography (PET) scanning showed high-intensity fludeoxyglucose (FDG) uptake in the mass in the upper left lobe (SUVmax of 9.7)
Figure 3. a–d
Figure 3. a–d
(a) Representative hematoxylin and eosin (HE) sections at original 4× magnification. Lesion created short bundles and consist of fusiform cells that show a storiform pattern (HE, 4×). (b) Bundles of malignant fusiform cells (HE,10×). (c) Tumor showed CD68 (+) immunoreactivity (HE,10×). (d) Tumor showed vimentin (+) immunoreactivity (HE, 10×)
See this image and copyright information in PMC

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