Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Feb;79(1):13-20.
doi: 10.1055/s-0037-1615815. Epub 2018 Jan 5.

Endoscopic Management of Developmental Anomalies of the Skull Base

Meghan Wilson  1 , Carl Snyderman  2
Affiliations
Review

Endoscopic Management of Developmental Anomalies of the Skull Base

Meghan Wilson et al. J Neurol Surg B Skull Base. 2018 Feb.

Abstract

Developmental anomalies of the skull base may present in childhood or as an adult. The most common pathologies include dermoid, encephalocele, and glioma. Encephaloceles may present as part of a syndrome. Other entities include infantile hemangiomas and teratoma. Endoscopic techniques provide a less invasive and morbid option for treatment. Proper evaluation and treatment is necessary to prevent complications such as meningitis.

Keywords: dermoid encephalocele; developmental; glioma; teratoma.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None.

Figures

Fig. 1
Fig. 1
Coronal ( A ) and sagittal ( B ) computed tomography (CT) demonstrate an expansive fat-density lesion (asterisk) extending to the skull base at foramen cecum (arrow) anterior to the crista galli.
Fig. 2
Fig. 2
Coronal ( A ) and sagittal ( B ) magnetic resonance imaging (MRI) demonstrate a large meningoencephalocele involving the right gyrus rectus and orbital gyrus (asterisk) and extending through a defect of the right cribriform plate (arrow) and filling the nasal cavity. There is deviation of the nasal septum from the large mass.
Fig. 3
Fig. 3
Axial computed tomography (CT) ( A ) demonstrates a left nasal mass (asterisk). Sagittal magnetic resonance imaging (MRI) ( B ) demonstrates an intranasal mass that extends to the skull base but there is no evidence of intracranial extension (arrow).
Fig. 4
Fig. 4
Example of a large teratoma involving the midface and anterior skull base ( A ). Three-dimensional (3D) reconstruction (different patient) demonstrates tumor protruding from the oral cavity ( B ). These tumors were resected using a transpalatal endoscopic endonasal approach.
See this image and copyright information in PMC

References

    1. Banu M A, Guerrero-Maldonado A, McCrea H J et al.Impact of skull base development on endonasal endoscopic surgical corridors. J Neurosurg Pediatr. 2014;13(02):155–169. - PubMed
    1. Tatreau J R, Patel M R, Shah R N et al.Anatomical considerations for endoscopic endonasal skull base surgery in pediatric patients. Laryngoscope. 2010;120(09):1730–1737. - PubMed
    1. Stapleton A L, Tyler-Kabara E C, Gardner P A, Snyderman C H, Wang E W. Risk factors for cerebrospinal fluid leak in pediatric patients undergoing endoscopic endonasal skull base surgery. Int J Pediatr Otorhinolaryngol. 2017;93:163–166. - PubMed
    1. Stapleton A L, Tyler-Kabara E C, Gardner P A, Snyderman C H. The costs of skull base surgery in the pediatric population. J Neurol Surg B Skull Base. 2015;76(01):39–42. - PMC - PubMed
    1. Kassam A, Thomas A J, Snyderman Cet al.Fully endoscopic expanded endonasal approach treating skull base lesions in pediatric patients J Neurosurg 2007106(2, Suppl)75–86. - PubMed