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Editorial
. 2018 Jul;68(1):13-15.
doi: 10.1002/hep.29831.

Hepatocellular carcinoma: Liver biopsy in the balance

David E Kleiner  1
Affiliations
Editorial

Hepatocellular carcinoma: Liver biopsy in the balance

David E Kleiner. Hepatology. 2018 Jul.

Abstract

The use of liver biopsy to diagnose hepatocellular carcinoma is governed by the balance of the risks of the procedure (morbidity, mortality, inadequate sampling), the relative utility of non-invasive techniques and the benefits of precise diagnosis, prognostic and theragnostic information and access to tissue for molecular analysis. In this issue of Hepatology, identification of the macrotrabecular subtype of hepatocellular carcinoma on liver biopsy is shown to add clinically useful prognostic information as well as molecular correlations.

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Conflict of interest statement

Conflict of interest disclosure: The author states that has no financial or other conflicts of interest with respect to this work.

Figures

Figure 1
Figure 1
Macrotrabecular hepatocellular carcinoma. The tumor is organized into wide plates of tumor cells separated by pseudo-sinusoidal spaces. The nuclei show moderate pleomorphism and hyperchromasia, consistent with high nuclear grade. This tumor also demonstrated microvascular invasion. (H&E, 200x)
See this image and copyright information in PMC

Comment on

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