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. 2018 Mar:116:221-226.
doi: 10.1016/j.micpath.2018.01.038. Epub 2018 Jan 31.

Synthesis of silver nanoparticles from Bacillus brevis (NCIM 2533) and their antibacterial activity against pathogenic bacteria

Muthupandian Saravanan  1 , Sisir Kumar Barik  2 , Davoodbasha MubarakAli  3 , Periyakaruppan Prakash  4 , Arivalagan Pugazhendhi  5
Affiliations

Synthesis of silver nanoparticles from Bacillus brevis (NCIM 2533) and their antibacterial activity against pathogenic bacteria

Muthupandian Saravanan et al. Microb Pathog. 2018 Mar.

Abstract

The present study is focused on the biological synthesis of silver nanoparticles (AgNPs) from the Bacillus brevis (NCIM 2533) was investigated. The synthesized AgNPs were characterized by various spectroscopic and microscopic techniques and confirmed the AgNPs having the surface Plasmon resonance peak at 420 nm and in the size range of 41-68 nm with spherical in shape by AFM and SEM analysis. It was confirmed and ascertained the presence of bioactive compounds in the AgNPs using TLC and FTIR. The In-vitro antibacterial activity of AgNPs showaed potential antibacterial property against multi-drug resistant pathogens such as Salmonella typhi and Staphylococcus aureus. The biosynthesized AgNPs could be utilized as antimicrobial agents for effective disease management.

Keywords: Antimicrobial activity; Bacillus brevis; Biosynthesis; Human pathogen; Multi-drug resistant; Silver nanoparticles.

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