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. 2018 May;28(3):383-408.
doi: 10.1080/14397595.2018.1438093. Epub 2018 Mar 13.

Clinical practice guideline for Sjögren's syndrome 2017

Takayuki Sumida  1   2 , Naoto Azuma  2   3 , Masafumi Moriyama  2   4 , Hiroyuki Takahashi  1   2 , Hiromitsu Asashima  1   2 , Fumika Honda  1 , Saori Abe  1 , Yuko Ono  1   4 , Tomoya Hirota  1   2 , Shintaro Hirata  2   5   6 , Yoshiya Tanaka  2   5 , Toshimasa Shimizu  2   7 , Hideki Nakamura  2   7 , Atsushi Kawakami  2   7 , Hajime Sano  2   3 , Yoko Ogawa  2   8 , Kazuo Tsubota  2   8 , Koufuchi Ryo  2   9 , Ichiro Saito  2   9 , Akihiko Tanaka  2   4 , Seiji Nakamura  2   4 , Etsuko Takamura  2   10 , Masao Tanaka  2   11 , Katsuya Suzuki  2   12 , Tsutomu Takeuchi  2   12 , Noriyuki Yamakawa  2   13   14 , Tsuneyo Mimori  2   13 , Akiko Ohta  2   15 , Susumu Nishiyama  2   16 , Toshio Yoshihara  2   17 , Yasunori Suzuki  2   18 , Mitsuhiro Kawano  2   18 , Minako Tomiita  2   19 , Hiroto Tsuboi  1   2
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Free article

Clinical practice guideline for Sjögren's syndrome 2017

Takayuki Sumida et al. Mod Rheumatol. 2018 May.
Free article

Abstract

Objectives: The objective of this study is to develop clinical practice guideline (CPG) for Sjögren's syndrome (SS) based on recently available clinical and therapeutic evidences.

Methods: The CPG committee for SS was organized by the Research Team for Autoimmune Diseases, Research Program for Intractable Disease of the Ministry of Health, Labor and Welfare (MHLW), Japan. The committee completed a systematic review of evidences for several clinical questions and developed CPG for SS 2017 according to the procedure proposed by the Medical Information Network Distribution Service (Minds). The recommendations and their strength were checked by the modified Delphi method. The CPG for SS 2017 has been officially approved by both Japan College of Rheumatology and the Japanese Society for SS.

Results: The CPG committee set 38 clinical questions for clinical symptoms, signs, treatment, and management of SS in pediatric, adult and pregnant patients, using the PICO (P: patients, problem, population, I: interventions, C: comparisons, controls, comparators, O: outcomes) format. A summary of evidence, development of recommendation, recommendation, and strength for these 38 clinical questions are presented in the CPG.

Conclusion: The CPG for SS 2017 should contribute to improvement and standardization of diagnosis and treatment of SS.

Keywords: Medical Information Network Distribution Service (Minds); Sjögren’s syndrome; clinical practice guideline; clinical question; systematic review.

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