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. 2018 Feb;23(5):17-00284.
doi: 10.2807/1560-7917.ES.2018.23.5.17-00284.

Seasonality and geographical spread of respiratory syncytial virus epidemics in 15 European countries, 2010 to 2016

Eeva K Broberg  1 , Matti Waris  2   3 , Kari Johansen  1 , René Snacken  1 , Pasi Penttinen  1 ; European Influenza Surveillance Network  4
Affiliations

Seasonality and geographical spread of respiratory syncytial virus epidemics in 15 European countries, 2010 to 2016

Eeva K Broberg et al. Euro Surveill. 2018 Feb.

Abstract

Respiratory syncytial virus (RSV) is considered the most common pathogen causing severe lower respiratory tract infections among infants and young children. We describe the seasonality and geographical spread of RSV infection in 15 countries of the European Union and European Economic Area. We performed a retrospective descriptive study of weekly laboratory-confirmed RSV detections between weeks 40/2010 and 20/2016, in patients investigated for influenza-like illness, acute respiratory infection or following the clinician's judgment. Six countries reported 4,230 sentinel RSV laboratory diagnoses from primary care and 14 countries reported 156,188 non-sentinel laboratory diagnoses from primary care or hospitals. The median length of the RSV season based on sentinel and non-sentinel surveillance was 16 (range: 9-24) and 18 (range: 8-24) weeks, respectively. The median peak weeks for sentinel and non-sentinel detections were week 4 (range: 48 to 11) and week 4.5 (range: 49 to 17), respectively. RSV detections peaked later (r = 0.56; p = 0.0360) and seasons lasted longer with increasing latitude (r = 0.57; p = 0.0329). Our data demonstrated regular seasonality with moderate correlation between timing of the epidemic and increasing latitude of the country. This study supports the use of RSV diagnostics within influenza or other surveillance systems to monitor RSV seasonality and geographical spread.

Keywords: RSV; geographic spread; respiratory syncytial virus; seasonality.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Non-sentinel (n = 14 countries) and sentinel (n = 6 countries) RSV detections by country, season and week of detection, EU/EEA, 2010–2016
Figure 2
Figure 2
Timing of RSV season as observed by non-sentinel (n = 14 countries) and sentinel (n = 6 countries) surveillance, EU/EEA, 2010–2016
Figure 3
Figure 3
Correlation between the RSV seasonal timing and geographical location of the reporting country, non-sentinel data, EU/EEA, 2010–2016 (n = 14 countries)
See this image and copyright information in PMC

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