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Review
. 2018 Feb;48(2):204-206.
doi: 10.1111/imj.13703.

Management of neurosyphilis: time for a new approach?

Olivia C Smibert  1   2 , Adam W J Jenney  1   2 , Denis W Spelman  1   2
Affiliations
Review

Management of neurosyphilis: time for a new approach?

Olivia C Smibert et al. Intern Med J. 2018 Feb.

Abstract

Given the long term sequelae of untreated neurosyphilis and insensitive tests to detect treponemes in the cerebrospinal fluid, questions regarding the utility of a lumbar puncture and cerebrospinal fluid analysis either to confirm or exclude neurosyphilis are raised.

Keywords: cerebrospinal fluid; neurosyphilis; rapid plasma reagin; syphilis; syphilis serology.

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