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Case Reports
. 2018 Feb;98(2):351-352.
doi: 10.4269/ajtmh.17-0574.

Metronidazole-Associated Encephalopathy

Daisuke Taniyama  1 , Taketomo Maruki  1
Affiliations
Case Reports

Metronidazole-Associated Encephalopathy

Daisuke Taniyama et al. Am J Trop Med Hyg. 2018 Feb.
No abstract available

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Figures

Figure 1.
Figure 1.
Fluid-attenuated inversion recovery magnetic resonance imaging after the start of metronidazole treatment. The scans after the start of metronidazole treatment reveal bilaterally symmetrical high signals in the (A) bulb olivary nucleus, (B) cerebellar dentate nucleus, (C) pons, and (D) splenium of the corpus callosum.
Figure 2.
Figure 2.
Fluid-attenuated inversion recovery magnetic resonance imaging after stopping metronidazole treatment. The scans 3 weeks after stopping the metronidazole treatment reveal resolution of bilaterally symmetrical high signals in the (A) bulb olivary nucleus, (B) cerebellar dentate nucleus, (C) pons, and (D) splenium of the corpus callosum.
See this image and copyright information in PMC

References

    1. Kapoor K, Chandra M, Nag D, Paliwal JK, Gupta RC, Saxena RC, 1999. Evaluation of metronidazole toxicity: a prospective study. Int J Clin Pharmacol Res 19: 83–88. - PubMed
    1. Huang YT, Chen LA, Cheng SJ, 2012. Metronidazole-induced encephalopathy: case report and review literature. Acta Neurol Taiwan 21: 74–78. - PubMed
    1. Kato H, Sosa H, Mori M, Kaneko T, 2015. Clinical characteristics of metronidazole-induced encephalopathy: a report of two cases and a review of 32 Japanese cases in the literature. Kansenshogaku Zasshi 89: 559–566 (in Japanese). - PubMed

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