Cardiorespiratory fitness versus physical activity as predictors of all-cause mortality in men
- PMID: 29421008
- DOI: 10.1016/j.ahj.2017.08.022
Cardiorespiratory fitness versus physical activity as predictors of all-cause mortality in men
Abstract
Background: Although both cardiorespiratory fitness (CRF) and physical activity (PA) are associated with mortality, whether they are associated with all-cause mortality independent of each other is unclear.
Methods: CRF was assessed by a maximal exercise test and PA was measured by self-report in 8,171 male veterans. The predictive power of CRF and PA, along with clinical variables, was assessed for all-cause mortality during a mean (±SD) follow-up 8.7 (4.4) years during which there were 1,349 deaths.
Results: CRF was associated with mortality after adjusting for clinical variables and remained a strong predictor of mortality after further adjusting for PA (hazard ratio 0.85, 95% CI 0.83-0.87). PA was a significant predictor of mortality after controlling for clinical variables; however, the association was eliminated after further adjusting for CRF (hazard ratio 0.98, 95% CI 0.88-1.10). In CRF-stratified analysis, being active (≥150 min/wk) was not associated with mortality within the unfit or fit categories (P>.4). However, in PA-stratified analysis, subjects categorized as fit (≥7 metabolic equivalents [METS]) had a lower risk of mortality regardless of PA status (P<.001).
Conclusions: In adult men, PA was associated with mortality independent of established risk factors, but not CRF. Conversely, CRF remained a strong predictor of mortality independent of PA status and established risk factors.
Crown Copyright © 2017. Published by Elsevier Inc. All rights reserved.
Comment in
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Arrival and survival of the fittest.Am Heart J. 2018 Feb;196:153-155. doi: 10.1016/j.ahj.2017.08.020. Epub 2017 Sep 1. Am Heart J. 2018. PMID: 29421007 No abstract available.
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