Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Feb;53(2):142-148.
doi: 10.1055/s-0043-114639. Epub 2018 Feb 9.

[SSC International Guideline 2016 - Management of Sepsis and Septic Shock]

[Article in German]
Tim Rahmel
Review

[SSC International Guideline 2016 - Management of Sepsis and Septic Shock]

[Article in German]
Tim Rahmel. Anasthesiol Intensivmed Notfallmed Schmerzther. 2018 Feb.

Abstract
in English, German

The new guideline of the Surviving Sepsis Campaign was revised in 2016 and presented in 2017. Furthermore, "Sepsis-3" in 2016 completely changed the definition of Sepsis from inflammation plus infection to a "life-threatening organ dysfunction caused by a dysregulated host response". To cope with the great challenge to unite the new evidence of sepsis treatment with the new definition of sepsis, the guidelines have been completely reconstructed and comprehensively deal with new evidence. The guidelines discuss sepsis-specific treatment and provide recommendations on general measures of intensive care for sepsis. The article summarizes the most important recommendations and additionally discusses some crucial amendments. This is intended to encourage the reader to incorporate the new guideline into clinical practice, thus improving the prognosis of patients suffering from sepsis or septic shock.

Die neue Leitlinie der Surviving Sepsis Campaign wurde im Jahr 2016 überarbeitet und im Jahr 2017 veröffentlicht. Darüber hinaus änderte sich durch „Sepsis-3“ die Definition der Sepsis im Jahr 2016 grundlegend, von einer Inflammation mit Infektion hin zu einer „lebensbedrohlichen Organ-Dysfunktion, die durch eine fehlregulierte Wirtsreaktion“ verursacht wird. Um die große Herausforderung zu bewältigen, die neuen Erkenntnisse zur Sepsisbehandlung mit der neuen Definition zu vereinen, wurden die Leitlinien vollständig neu strukturiert und umfassend überarbeitet. Die Leitlinie diskutiert die sepsisspezifische Behandlung und gibt Empfehlungen für allgemeine intensivmedizinische Maßnahmen. Der Artikel fasst die wichtigsten Empfehlungen zusammen und diskutiert zusätzlich einige entscheidende Änderungen. Dies soll den Leser ermutigen, die neue Leitlinie in den klinischen Alltag zu übernehmen und somit die Prognose der Patienten, die an einer Sepsis oder einem septischem Schock leiden, zu verbessern.

PubMed Disclaimer

Conflict of interest statement

Die Autoren erklären, dass kein Interessenkonflikt vorliegt.

Similar articles

  • [International guidelines from the Surviving Sepsis Campaign : 2016 update].
    Briegel J, Möhnle P. Briegel J, et al. Anaesthesist. 2017 Jul;66(7):530-538. doi: 10.1007/s00101-017-0299-z. Anaesthesist. 2017. PMID: 28364305 Review. German.
  • The management of severe sepsis and septic shock.
    Morrell MR, Micek ST, Kollef MH. Morrell MR, et al. Infect Dis Clin North Am. 2009 Sep;23(3):485-501. doi: 10.1016/j.idc.2009.04.002. Infect Dis Clin North Am. 2009. PMID: 19665079 Review.
  • Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
    Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Weiss SL, et al. Pediatr Crit Care Med. 2020 Feb;21(2):e52-e106. doi: 10.1097/PCC.0000000000002198. Pediatr Crit Care Med. 2020. PMID: 32032273
  • Surviving Sepsis Campaign: Research Priorities for Sepsis and Septic Shock.
    Coopersmith CM, De Backer D, Deutschman CS, Ferrer R, Lat I, Machado FR, Martin GS, Martin-Loeches I, Nunnally ME, Antonelli M, Evans LE, Hellman J, Jog S, Kesecioglu J, Levy MM, Rhodes A. Coopersmith CM, et al. Crit Care Med. 2018 Aug;46(8):1334-1356. doi: 10.1097/CCM.0000000000003225. Crit Care Med. 2018. PMID: 29957716
  • Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
    Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP. Rhodes A, et al. Intensive Care Med. 2017 Mar;43(3):304-377. doi: 10.1007/s00134-017-4683-6. Epub 2017 Jan 18. Intensive Care Med. 2017. PMID: 28101605
See all similar articles

Cited by

See all "Cited by" articles

MeSH terms

LinkOut - more resources