Post-contrast acute kidney injury - Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines
- PMID: 29426991
- PMCID: PMC5986826
- DOI: 10.1007/s00330-017-5246-5
Post-contrast acute kidney injury - Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines
Abstract
Purpose: The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 2011 guidelines on the prevention of post-contrast acute kidney injury (PC-AKI). The results of the literature review and the recommendations based on it, which were used to prepare the new guidelines, are presented in two papers. AREAS COVERED IN PART 1: Topics reviewed include the terminology used, the best way to measure eGFR, the definition of PC-AKI, and the risk factors for PC-AKI, including whether the risk with intravenous and intra-arterial contrast medium differs.
Key points: • PC-AKI is the preferred term for renal function deterioration after contrast medium. • PC-AKI has many possible causes. • The risk of AKI caused by intravascular contrast medium has been overstated. • Important patient risk factors for PC-AKI are CKD and dehydration.
Keywords: Acute kidney injury; Contrast media; Glomerular filtration rate; Practice guidelines as topic; Risk factors.
Conflict of interest statement
Guarantor
The scientific guarantor of this publication is Prof. Henrik S. Thomsen.
Conflict of interest
Aart van der Molen has received incidental payments for lectures and chairmanships at scientific meetings for contrast agent safety related issues (contrast agent reactions, Gd-retention) from GE, Bayer, Bracco and Guerbet
Fulvio Stacul has received lecture fees from Bracco and Guerbet
Olivier Clément has received lecture fees from Bracco and Guerbet
The other authors of this manuscript declare no relationships with any companies whose products and services may be related to the subject matter of this article.
References
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- Morcos SK, Thomsen HS, Webb JA, Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) et al. Dialysis and contrast media. Eur Radiol. 2002;12:3026–3030. - PubMed
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- Contrast Media Safety Committee ESUR. Guidelines on Contrast Media v9. CMSC, 2014. Available via: http://www.esur-cm.org/index.php/en/ Accessed: 14 December 2017
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- Gruberg L, Mintz GS, Mehran R, et al. The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. J Am Coll Cardiol. 2000;36:1542–1548. doi: 10.1016/S0735-1097(00)00917-7. - DOI - PubMed
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