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Comment
. 2018 Aug;68(2):777-779.
doi: 10.1002/hep.29839. Epub 2018 May 14.

The ABC of adaptive immunity in liver cancer

Tim F Greten  1
Affiliations
Comment

The ABC of adaptive immunity in liver cancer

Tim F Greten. Hepatology. 2018 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Potential conflict of interest: Nothing to report.

Comment on

  • Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.
    Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. Shalapour S, et al. Nature. 2017 Nov 16;551(7680):340-345. doi: 10.1038/nature24302. Epub 2017 Nov 8. Nature. 2017. PMID: 29144460 Free PMC article.

References

    1. Shalapour S, Lin X-J, Bastian IN, Brain J, Burt AD, Aksenov AA, et al. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature 2017;551:340–345. - PMC - PubMed
    1. Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, et al. Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy. Nature 2015;521:94–98. - PMC - PubMed
    1. Faggioli F, Palagano E, Di Tommaso L, Donadon M, Marrella V, Recordati C, et al. B lymphocytes limit senescence-driven fibrosis resolution and favor hepatocarcinogenesis in mouse liver injury. HEPATOLOGY 2017; doi:10.1002/hep.29636. - DOI - PubMed
    1. Wolf MJ, Adili A, Piotrowitz K, Abdullah Z, Boege Y, Stemmer K, et al. Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes. Cancer Cell 2014;26:549–564. - PubMed
    1. Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol 2015;16:1235–1244. - PMC - PubMed

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