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. 2017 Nov 30;7(3):419-429.
doi: 10.1159/000484137. eCollection 2017 Sep-Dec.

Lexical Retrieval or Semantic Knowledge? Which One Causes Naming Errors in Patients with Mild and Moderate Alzheimer's Disease?

Masoome Salehi  1 , Mohsen Reisi  2 , Leila Ghasisin  3
Affiliations

Lexical Retrieval or Semantic Knowledge? Which One Causes Naming Errors in Patients with Mild and Moderate Alzheimer's Disease?

Masoome Salehi et al. Dement Geriatr Cogn Dis Extra. .

Abstract

Background: The purpose of the study was to analyze naming errors in patients with Alz-heimer's disease in comparison to healthy subjects and determine the underlying cause of naming errors in these patients.

Method: In this study, we included 35 healthy elderly subjects, 23 patients with mild Alzheimer's disease, and 23 with moderate Alzheimer's disease. Forty-five images were used to determine the type of naming errors, and to identify the underlying cause of errors, matching an image with a written word was used.

Results: Patients with Alz-heimer's disease had more naming errors compared with the group of healthy elderly, and patients with moderate Alzheimer's disease showed a slower reaction in matching an image with a written word.

Conclusion: Anomia in the initial phase of Alzheimer's disease is due to problems in lexical retrieval; however, as the disease advances, in addition to lexical retrieval problems, conceptual knowledge causes naming problems.

Keywords: Alzheimer's disease; Anomia; Conceptual knowledge; Lexical retrieval; Phonological layer; Semantic layer.

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