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Review
. 2017 Dec 21;7(3):440-452.
doi: 10.1159/000485178. eCollection 2017 Sep-Dec.

Hearing Impairment, Mild Cognitive Impairment, and Dementia: A Meta-Analysis of Cohort Studies

Jingkai Wei  1 , Yirui Hu  2 , Li Zhang  3 , Qiang Hao  4 , Ruowei Yang  5 , Haidong Lu  1 , Xuan Zhang  6 , Eeshwar K Chandrasekar  7
Affiliations
Review

Hearing Impairment, Mild Cognitive Impairment, and Dementia: A Meta-Analysis of Cohort Studies

Jingkai Wei et al. Dement Geriatr Cogn Dis Extra. .

Abstract

Background: To estimate a pooled association between hearing impairment and risk of mild cognitive impairment and dementia.

Methods: PubMed, Embase, and Web of Science were searched for prospective cohort studies that examined the association between hearing impairment and risk of mild cognitive impairment and/or dementia. Random-effects models were fitted to estimate the summary risk ratios (RRs) and 95% confidence interval (CIs), which represents the pooled association between hearing impairment with risk of mild cognitive impairment and dementia, compared to subjects free of hearing impairment.

Results: Four studies on hearing impairment with mild cognitive impairment and 7 studies on hearing impairment with dementia were included in the meta-analysis. A total of 15,521 subjects were studied with follow-up periods between 2 and 16.8 years. Hearing impairment was associated with a greater risk of mild cognitive impairment (RR = 1.30, 95% CI: 1.12, 1.51) and dementia (RR = 2.39, 95% CI: 1.58, 3.61).

Conclusions: The meta-analysis showed that hearing impairment is associated with a higher risk of mild cognitive impairment and dementia among older adults.

Keywords: Dementia; Hearing impairment; Meta-analysis; Mild cognitive impairment.

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Figures

Fig. 1.
Fig. 1.
Flowchart showing selection of study reports for the meta-analysis.
Fig. 2.
Fig. 2.
Forest plot of the associations between hearing impairment and risk of MCI.
Fig. 3.
Fig. 3.
Forest plot of the associations between hearing impairment and risk of dementia.
See this image and copyright information in PMC

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