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Review
. 2018 Feb 6;9(1):1-7.
doi: 10.4292/wjgpt.v9.i1.1.

Monitoring inflammatory bowel disease during pregnancy: Current literature and future challenges

Tenzin Choden  1 , Rohan Mandaliya  2 , Aline Charabaty  2 , Mark C Mattar  2
Affiliations
Review

Monitoring inflammatory bowel disease during pregnancy: Current literature and future challenges

Tenzin Choden et al. World J Gastrointest Pharmacol Ther. .

Abstract

Inflammatory bowel disease has a high prevalence in women of childbearing age and can have a significant impact on pregnancy, from conceiving to carrying the pregnancy. Active disease during pregnancy is known to have negative effects on pregnancy outcomes; therefore, careful monitoring during this period is an important but challenging aspect of care and is crucial as it affects important management decisions. Recent data seems to suggest that endoscopy is a relatively safe procedure during all trimesters of pregnancy. Serum biomarkers such as C-reactive protein and fecal calprotectin are helpful non-invasive markers, but have shown conflicting results for correlation with disease activity in some initial studies. Further work is necessary to establish standard of care monitoring during pregnancy.

Keywords: Crohn’s disease; Fecal calprotectin; Inflammatory bowel disease; Pregnancy; Ulcerative colitis.

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Conflict of interest statement

Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.

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