Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 Feb 5;190(5):E124-E125.
doi: 10.1503/cmaj.180076.

Whole genome sequencing in the clinic: empowerment or too much information?

Amanda J Berberich  1 , Rosettia Ho  1 , Robert A Hegele  2
Affiliations
Comment

Whole genome sequencing in the clinic: empowerment or too much information?

Amanda J Berberich et al. CMAJ. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: Robert Hegele has received honorariums for membership on advisory boards and speakers’ bureaus for Akcea and Ionis, Aegerion Pharmaceuticals, Amgen, Gemphire Therapeutics, Regeneron Pharmaceuticals, Sanofi and Valeant, outside the submitted work. No other competing interests were declared. This article was solicited and has not been peer reviewed.

Comment on

  • The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants.
    Reuter MS, Walker S, Thiruvahindrapuram B, Whitney J, Cohn I, Sondheimer N, Yuen RKC, Trost B, Paton TA, Pereira SL, Herbrick JA, Wintle RF, Merico D, Howe J, MacDonald JR, Lu C, Nalpathamkalam T, Sung WWL, Wang Z, Patel RV, Pellecchia G, Wei J, Strug LJ, Bell S, Kellam B, Mahtani MM, Bassett AS, Bombard Y, Weksberg R, Shuman C, Cohn RD, Stavropoulos DJ, Bowdin S, Hildebrandt MR, Wei W, Romm A, Pasceri P, Ellis J, Ray P, Meyn MS, Monfared N, Hosseini SM, Joseph-George AM, Keeley FW, Cook RA, Fiume M, Lee HC, Marshall CR, Davies J, Hazell A, Buchanan JA, Szego MJ, Scherer SW. Reuter MS, et al. CMAJ. 2018 Feb 5;190(5):E126-E136. doi: 10.1503/cmaj.171151. CMAJ. 2018. PMID: 29431110 Free PMC article.

References

    1. Reuter MS, Walker S, Thiruvahindrapuram B, et al. Personal Genome Project Canada: findings from the whole genome sequences of the inaugural 56 participants. CMAJ 2018;190:E126–36. - PMC - PubMed
    1. Ball MP, Bobe JR, Chou MF, et al. Harvard Personal Genome Project: lessons from participatory public research. Genome Med 2014;6:10. - PMC - PubMed
    1. Bick D, Dimmock D. Whole exome and whole genome sequencing. Curr Opin Pediatr 2011;23:594–600. - PubMed
    1. Farhan SM, Hegele RA. Genetics 101 for cardiologists: rare genetic variants and monogenic cardiovascular disease. Can J Cardiol 2013;29:18–22. - PubMed
    1. Boycott KM, Vanstone MR, Bulman DE, et al. Rare-disease genetics in the era of next-generation sequencing: discovery to translation. Nat Rev Genet 2013;14:681–91. - PubMed