Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Feb 13;11(1):122.
doi: 10.1186/s13104-018-3220-1.

Histopathologic characteristics of biopsies from dogs undergoing surgery with concurrent gross splenic and hepatic masses: 125 cases (2012-2016)

Affiliations

Histopathologic characteristics of biopsies from dogs undergoing surgery with concurrent gross splenic and hepatic masses: 125 cases (2012-2016)

Fernando J Leyva et al. BMC Res Notes. .

Abstract

Objective: To investigate the histopathologic characteristics of concurrent splenic and liver masses in dogs undergoing splenectomy and liver mass biopsy/resection. Medical records of 125 client-owned dogs found to have splenic mass or masses and a liver mass or masses during surgery were examined. Signalment (age, sex, breed), body weight, and results of histopathology were recorded for all dogs.

Results: Twenty-seven percent (34/125) of the dogs in this study had no evidence of malignancy in either the liver or the spleen. Sixty of 125 dogs (48.0%) had malignancy in the spleen and liver, and 56 (56/60, 93.3%) of those dogs had the same malignancy in both organs. Signalment was similar to that in other reports of splenic pathology. In this clinical population of dogs, 27% of dogs with concurrent gross splenic and liver masses discovered intraoperatively had benign lesions in both locations and therefore had a favorable prognosis.

Keywords: Canine biopsies; Dog biopsies; Hemangiosarcoma; Hepatic mass; Histopathology; Splenic mass.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Numbers and percentages of benign and malignant SM and HM (n = 125)

References

    1. Day MJ, Lucke VM, Pearson H. A review of pathological diagnoses made from 87 canine splenic biopsies. J Small Anim Pract. 1995;36:426–433. doi: 10.1111/j.1748-5827.1995.tb02769.x. - DOI - PubMed
    1. Spangler WL, Culbertson MR. Prevalence, type, and importance of splenic diseases in dogs: 1,480 cases (1985–1989) J Am Vet Med Assoc. 1992;200:829–834. - PubMed
    1. Spangler WL, Kass PH. Pathologic factors affecting postsplenectomy survival in dogs. J Vet Intern Med. 1997;11:166–171. doi: 10.1111/j.1939-1676.1997.tb00085.x. - DOI - PubMed
    1. Cleveland MJ, Casale S. Incidence of malignancy and outcomes for dogs undergoing splenectomy for incidentally detected nonruptured splenic nodules or masses: 105 cases (2009–2013) J Am Vet Med Assoc. 2016;248:1267–1273. doi: 10.2460/javma.248.11.1267. - DOI - PubMed
    1. Johnson KA, Powers BE, Withrow SJ, et al. Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy. J Vet Intern Med. 1989;3:160–166. doi: 10.1111/j.1939-1676.1989.tb03092.x. - DOI - PubMed