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. 2018 Feb 13;23(2):409.
doi: 10.3390/molecules23020409.

Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers

Mihai Babotă  1 , Andrei Mocan  2 , Laurian Vlase  3 , Ovidiu Crișan  4 , Irina Ielciu  5 , Ana-Maria Gheldiu  6 , Dan Cristian Vodnar  7 , Gianina Crișan  8 , Ramona Păltinean  9
Affiliations

Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers

Mihai Babotă et al. Molecules. .

Abstract

Antennaria dioica (L.) Gaertn. and Helichrysum arenarium (L.) Moench. are two species of the Asteraceae family, known in Romanian traditional medicine for their diuretic, choleretic, and anti-inflammatory properties. The aim of the present study was to evaluate the phenolic and sterolic composition of flowers from the two species and to assess their antioxidant, antibacterial and antifungal properties. LC-MS analyses were performed on methanolic, ethanolic and 70% v/v ethanolic extracts, before and after acid hydrolysis, and revealed high amounts of polyphenols. Chlorogenic acid was found as the main compound for the flowers of A. dioica (502.70 ± 25.11 mg/100 g d.w.), while quercitrin was dominant in H. arenarium (424.28 ± 21.21 mg/100 g d.w.) in 70% v/v ethanolic extracts before hydrolysis. Antioxidant capacity assays showed an important antioxidant potential, which can be correlated with the determined polyphenolic compounds, showing the 70% v/v ethanolic extracts of the two species as being the most effective antioxidant samples for the DPPH assay. Antibacterial and antifungal assays confirm a modest biological potential for the same extract of both species. Results obtained in the present study bring important data and offer scientific evidence on the chemical composition and on the biological activities of the flowers belonging to the two species.

Keywords: A. dioica; H. arenarium; LC-MS; antibacterial activity; antifungal activity; antioxidant capacity; polyphenolic profile.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Helichrysum arenarium (L.) and Antennaria dioica (L.) Gaertn.
Figure 2
Figure 2
Total phenolic content (TPC) of H. arenarium and A. dioica flowers.
Figure 3
Figure 3
Total flavonoid content (TFC) of H. arenarium and A. dioica species.
See this image and copyright information in PMC

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