Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Feb 11;7(2):31.
doi: 10.3390/jcm7020031.

Canaloplasty in Corticosteroid-Induced Glaucoma. Preliminary Results

Paolo Brusini  1 , Claudia Tosoni  2 , Marco Zeppieri  3
Affiliations

Canaloplasty in Corticosteroid-Induced Glaucoma. Preliminary Results

Paolo Brusini et al. J Clin Med. .

Abstract

Purpose: to present the mid-term results of canaloplasty in a small cohort of corticosteroid glaucoma patients.

Material and methods: Nine eyes from seven patients with various types of corticosteroid glaucoma in maximum medical therapy underwent canaloplasty. Patients underwent complete ophthalmic examination every six months. Success was defined as: post-operative intraocular pressure (IOP) ≤ 21 mmHg and ≤ 16 mmHg without ("complete success"), and with/without medical treatment ("qualified success"). The IOP reduction had to be ≥ 20. The number of medications before and after surgery was considered. The follow-up mean period was 32.7 ± 20.8 months (range 14-72 months).

Results: The pre-operative mean IOP was 30.7 ± 7.2 mmHg (range: 24-45). The mean IOP at 6 and 12-month follow-up was 13.1 ± 2.6 mmHg, and 13.7 ± 1.9 mmHg, respectively. Qualified and complete success at 6 and 12 months was 100% for both of the two definitions. The number of medications used preoperatively and at the 12-month follow-up was 4.3 ± 0.7, and 0.2 ± 1.0, respectively. No serious complication was observed.

Conclusions: The mid-term results of canaloplasty in patients with corticosteroid-induced glaucoma appear to be very promising. Canaloplasty should be considered as a possible alternative to filtering surgery in this form of glaucoma, when medical therapy is not sufficient to maintain the IOP within reasonable limits.

Keywords: Schlemm’s canal; canaloplasty; corticosteroid-induced glaucoma; non-perforating surgical procedures.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Pre- and one-year post-operative IOP values.
See this image and copyright information in PMC

References

    1. McDonnell P.J., Kerr Muir M.G. Glaucoma associated with systemic corticosteroid therapy. Lancet. 1985;17:386–387. doi: 10.1016/S0140-6736(85)92519-X. - DOI - PubMed
    1. Kersey J.P., Broadway D.C. Corticosteroid-induced glaucoma: A review of the literature. Eye (Lond.) 2006;20:407–416. doi: 10.1038/sj.eye.6701895. - DOI - PubMed
    1. Kiddee W., Trope G.E., Sheng L., Beltran-Agullo L., Smith M., Strungaru M.H., Baath J., Buys Y.M. Intraocular pressure monitoring post intravitreal steroids: A systematic review. Surv. Ophthalmol. 2013;58:291–310. doi: 10.1016/j.survophthal.2012.08.003. - DOI - PubMed
    1. Jain S., Thompson J.R., Foot B., Tatham A., Eke T. Severe intraocular pressure rise following intravitreal triamcinolone: A national survey to estimate incidence and describe case profiles. Eye (Lond.) 2014;28:399–401. doi: 10.1038/eye.2013.306. - DOI - PMC - PubMed
    1. Mazzarella S., Mateo C., Freixes S., Burés-Jelstrup A., Rios J., Navarro R., García-Arumí J., Corcóstegui B., Arrondo E. Effect of intravitreal injection of dexamethasone 0.7 mg (Ozurdex®) on intraocular pressure in patients with macular edema. Ophthalmic Res. 2015;54:143–149. doi: 10.1159/000438759. - DOI - PubMed

LinkOut - more resources