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Review
. 2018 Jan-Mar;24(1):104-111.
doi: 10.4103/IJPC.IJPC_146_17.

Quality of Life of patients with chronic kidney disease in Iran: Systematic Review and Meta-analysis

Bahareh Ghiasi  1 , Diana Sarokhani  2 , Ali Hasanpour Dehkordi  3   4 , Kourosh Sayehmiri  5 , Mohammad Hossein Heidari  6
Affiliations
Review

Quality of Life of patients with chronic kidney disease in Iran: Systematic Review and Meta-analysis

Bahareh Ghiasi et al. Indian J Palliat Care. 2018 Jan-Mar.

Abstract

Introduction: Renal diseases are among the major health problems around the world that cause major changes in patients' lifestyle and affect their quality of lives. The aim of this study was to evaluate the quality of life of patients with chronic kidney disease (CKD) in Iran through a meta-analysis.

Materials and methods: This study was conducted using authentic Persian and English keywords in the national and international databases including IranMedex, SID, Magiran, IranDoc, Medlib, Science Direct, Pubmed, Scopus, Cochrane, Embase, Web of Science, and Medline. The data were analyzed using meta-analysis (random effects model). Heterogeneity of studies was assessed using I2 index. In this study, SF-36: 36-Item Short Form health-related quality of life (HRQOL), kidney disease quality of life-SF (KDQOL-SF), KDQOL and KDQOL-SFTM questionnaires were used. Data were analyzed using STATA Version 11 software.

Results: A total of 17200 individuals participated in 45 reviewed studies, and the mean score of CKD patients' quality of life was estimated by SF-36 (60.31), HRQOL (60.51), and KDQOL-SF (50.37) questionnaires. In addition, meta-regression showed that the mean score of CKD patients' quality of life did not significantly decrease during the past years.

Conclusion: The mean score of quality of life of patients with CKD was lower in different dimensions in comparison with that of normal people. Therefore, interventional measures should be taken to improve the quality of life of these patients in all dimensions.

Keywords: Iran; kidney patients; meta-analysis; quality of life; renal patients.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Chart 1
Chart 1
Flowchart of steps involved in entering the studies into the systematic review and meta-analysis process
Figure 1
Figure 1
Average quality of life in patients with chronic kidney disease in Iran (95% confidence interval) based on questionnaire according to random effects model. The middle point of each segment shows the quality of life score in chronic kidney disease patients in each study
Figure 2
Figure 2
The relationship between quality of life in chronic kidney disease patients and number of research samples using meta-regression
Figure 3
Figure 3
The relationship between quality of life in patients with chronic kidney disease and years of research using meta-regression
See this image and copyright information in PMC

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