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Case Reports
. 2018 Feb 1:10:177-180.
doi: 10.2147/CMAR.S145332. eCollection 2018.

Adrenal myelolipoma with hyperandrogenemia and schizophrenia

Ningning Liu #  1   2 , Wenhua Zhang #  3 , Jiangshan Tan  1   4 , Jiaxin Zhou  1 , Xiaopeng Yu  5 , Ningxin Ren  5 , Zhiqing Fang  3 , Wei Jiao  3 , Yidong Fan  3 , Cheng Liu  6
Affiliations
Case Reports

Adrenal myelolipoma with hyperandrogenemia and schizophrenia

Ningning Liu et al. Cancer Manag Res. .

Abstract

Adrenal myelolipoma with hyperandrogenemia is extremely rare. We report a case of a 26-year-old Chinese female with schizophrenia, who presented with a hormonally active tumor causing hyperandrogenemia. The mass was found by computerized tomography when she had her gynecologic examination for secondary amenorrhea, and it was confirmed to be an adrenal myelolipoma after a histopathological study. She was referred for a left adrenal laparoscopic excision, and the size of adrenal myelolipoma was found to be more than 10 cm. We report this case because large adrenal myelolipomas with hyperandrogenemia and schizophrenia are rare, and adrenal myelolipoma associated with hyperandrogenemia might be determined by the enzymes involved in the production of hormones.

Keywords: adrenal; hyperandrogenemia; myelolipoma; schizophrenia.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Coronal image from contrast-enhanced CT showing a left adrenal mass; left kidney is displaced inferiorly by the mass. Abbreviation: CT, computerized tomography.
Figure 2
Figure 2
Axial plane showing adipose tissue and septations. Notes: Tiny foci of calcifications are also visible in the lateral wall of the mass.
Figure 3
Figure 3
Low-power histological image showing a mixture of mature adipose tissue and bone marrow elements (×10).
Figure 4
Figure 4
The patient was referred for a left adrenal laparoscopic excision on August 22, 2016. Notes: After the surgery, her plasma testosterone level was back to normal.
See this image and copyright information in PMC

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