Efficacy of platelet transfusion for acute intracerebral hemorrhage among patients on antiplatelet therapy
- PMID: 29441841
- DOI: 10.1017/cem.2017.438
Efficacy of platelet transfusion for acute intracerebral hemorrhage among patients on antiplatelet therapy
Abstract
Clinical questionIn patients taking antiplatelet therapy, does a platelet transfusion after acute spontaneous primary intracerebral hemorrhage reduce the risk of death or dependence?Article chosenBaharoglu MI, Cordonnier C, Al-Shahi Salman R, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral hemorrhage associated with antiplatelet therapy (PATCH): a randomized, open-label, phase 3 trial. Lancet 2016;387(10038):2605-13.Study objectiveThe primary objective of this study was to investigate whether a platelet transfusion with standard care, compared with standard care alone, reduced death or dependence after intracerebral hemorrhage associated with antiplatelet therapy use.
Keywords: PATCH; antiplatelet therapy; intracerebral hemorrhage; platelet transfusion.
Comment on
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Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.Lancet. 2016 Jun 25;387(10038):2605-2613. doi: 10.1016/S0140-6736(16)30392-0. Epub 2016 May 10. Lancet. 2016. PMID: 27178479 Clinical Trial.
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