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Comment
. 2018 Feb 27;115(9):1962-1963.
doi: 10.1073/pnas.1800248115. Epub 2018 Feb 14.

Capturing bovine pluripotency

Ye Yuan  1
Affiliations
Comment

Capturing bovine pluripotency

Ye Yuan. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Balancing the stem-cell seesaw, a theory to explain how FGF signaling and WNT inhibition recapitulate pluripotency in cattle. Under standard primed culture condition, the potential bESC differentiate into mesendoderm cells in response to FGF and endogenous WNT. Bogliotti et al. (5) demonstrate the primed-state bESC can be stabilized by FGF2 supplementation and inhibition of WNT. The balance of lineage specification can result in a stabilized pluripotency state in cattle. Modified with permission from ref. .
See this image and copyright information in PMC

Comment on

References

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