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Review
. 2018 May;32(5):915-923.
doi: 10.1038/s41433-018-0033-3. Epub 2018 Feb 15.

The thick and thin of the central corneal thickness in glaucoma

Affiliations
Review

The thick and thin of the central corneal thickness in glaucoma

Graham W Belovay et al. Eye (Lond). 2018 May.

Abstract

Central corneal thickness (CCT) is an important parameter in the assessment of any potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in patients diagnosed with glaucoma is less certain. There are several biological factors and genetic components that may influence glaucoma progression, which have been associated with thinner CCT. The CCT itself can be affected by several factors including ethnicity, age, sex, glaucoma medications, genetics, and the subtype of glaucoma. Besides, there is variability in the measurement of CCT between difference types of devices. These factors need to be considered in the evaluation of glaucoma patients' CCT and its effect on interpretation of intraocular pressure levels and risk stratification.

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Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Bao F, Wang Q, Cheng S, Savini G, Lu W, Feng Y, et al. Comparison and evaluation of central corneal thickness using 2 new noncontact specular microscopes and conventional pachymetry devices. Cornea. 2014;33:576–81. - PubMed
    1. Borrego-Sanz L, Saenz-Frances F, Bermudez-Vallecilla M, Morales-Fernandez L, Martinez-de-la-Casa JM, Santos-Bueso E, et al. Agreement between central corneal thickness measured using pentacam, ultrasound pachymetry, specular microscopy and optic biometer lenstar is 900 and the influence of lntraocular pressure. Ophthalmologica. 2014;231:226–35. - PubMed
    1. Nam SM, Im CY, Lee HK, Kim EK, Kim T-i, Seo KY. Accuracy of RTVue optical coherence tomography, pentacam, and ultrasonic pachymetry for the measurement of central corneal thickness. Ophthalmology. 2010;117:2096–103. - PubMed
    1. Garcia-Medina JJ, Garcia-Medina M, Garcia-Maturana C, Zanon-Moreno V, Pons-Vazquez S, Pinazo-Duran MD. Comparative study of central corneal thickness using fourier-domain optical coherence tomography versus ultrasound pachymetry in primary open-angle glaucoma. Cornea. 2013;32:9–13. - PubMed
    1. Ang M, Chong W, Huang H, Tay WT, Wong TY, He MG, et al. Comparison of anterior segment optical tomography parameters measured using a semi-automatic software to standard clinical instruments. PLoS ONE. 2013;8:e65559. - PMC - PubMed