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Case Reports
. 2017 Dec 22;6(2):274-277.
doi: 10.1002/ccr3.1312. eCollection 2018 Feb.

A low-grade astrocytoma in a sixteen-year-old boy with a 7q11.22 deletion

Francoise S van Kampen  1 , Marianne E Doornbos  1 , Monique A van Rijn  2 , Yolande den Bever  3
Affiliations
Case Reports

A low-grade astrocytoma in a sixteen-year-old boy with a 7q11.22 deletion

Francoise S van Kampen et al. Clin Case Rep. .

Abstract

We report a patient with developmental delay due to germline AUTS2 mutation who developed a low-grade astrocytoma. While the contribution of this mutation to the pathogenesis of the tumor is not known at this time, a role of AUTS2 in deregulation of PRC1 can be a part in tumorigenesis of a brain tumor.

Keywords: AUTS2; brain tumor; neurologic; pediatric.

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Figures

Figure 1
Figure 1
(A) Flair image with hyperintense lesion in the right temporal lobe (indicated by an arrow). (B) Flair image with hyperintense lesion in the right temporal lobe (indicated by a red line).
Figure 2
Figure 2
Photomicrograph of the tumour histology.
See this image and copyright information in PMC

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