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Comment
. 2018 Apr 15;596(8):1315-1316.
doi: 10.1113/JP275704. Epub 2018 Mar 25.

Allegro giusto: piccolo, bassoon and clarinet set the tempo of vesicle pool replenishment

Andre Dagostin  1 , Christopher Kushmerick  2 , Henrique von Gersdorff  1
Affiliations
Comment

Allegro giusto: piccolo, bassoon and clarinet set the tempo of vesicle pool replenishment

Andre Dagostin et al. J Physiol. .
No abstract available

Keywords: auditory brainstem; bassoon; electrophysiology; piccolo; synapse; synaptic vesicle.

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Figures

Figure 1
Figure 1. Fast recovery from short‐term depression at an auditory synapse
A, excitatory postsynaptic currents (EPSCs) were evoked by afferent fibre stimulation at 100 Hz, which drives the immature (postnatal day 9 rat pup; pre‐hearing) calyx of Held synapse into short‐term depression. B, recovery from depression occurred in two exponential phases: a fast phase (τf = 40 ms, 28% of recovery) and a slow phase (τs = 0.5 s; Kushmerick et al. 2006). Temperature was 35°C. The average quantal size (mEPSC amplitude) is about 80 pA, so quantal content of the first EPSC was 250 vesicles released over 500–600 active zones.
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References

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