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Review
. 2018 May;18(5):1068-1076.
doi: 10.1111/ajt.14697. Epub 2018 Mar 30.

Reproductive health in women following abdominal organ transplant

Monika Sarkar  1 , Kate Bramham  2 , Michael J Moritz  3   4   5 , Lisa Coscia  3
Affiliations
Review

Reproductive health in women following abdominal organ transplant

Monika Sarkar et al. Am J Transplant. 2018 May.

Abstract

Fertility is commonly impaired in women with end-stage kidney and liver disease, although most women will have restoration of fertility within 1 year of transplant. Family planning is therefore critical to discuss with reproductive-aged transplant recipients in the early posttransplant period, in order to ensure timely initiation of contraception, and optimal timing for conception. For women seeking pregnancy, the risks to the mother, graft, and baby should be discussed, including evaluation of immunosuppression safety and potential for adjusting medications prior to conception. With an increasing number of transplant patients now breastfeeding, immunosuppression safety in lactation continues to carry great importance.

Keywords: clinical research/practice; kidney disease; kidney transplantation/nephrology; liver disease; liver transplantation/hepatology; obstetrics and gynecology; patient safety; pregnancy; reproductive biology.

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Conflict of interest statement

DISCLOSURE

The authors of this manuscript have conflicts of interest to disclose as described by the American Journal of Transplantation. Veloxis, Bristol-Meyers-Squibb, and Astellas Pharma, US, Inc have provided research support to Lisa Coscia and Michael Moritz. The other authors have no conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Centers for Disease Control recommendations for contraception use after solid organ transplant. CHC, combined hormonal contraception; DMPA, depot medroxyprogesterone acetate; IUD, intrauterine device; POP, progestin-only pill
FIGURE 2
FIGURE 2
Temporal trends in breastfeeding within the Transplant Pregnancy Registry International
See this image and copyright information in PMC

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