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Review
. 2018 May 24;399(6):525-547.
doi: 10.1515/hsz-2017-0329.

The AGO proteins: an overview

Saife Niaz  1
Affiliations
Review

The AGO proteins: an overview

Saife Niaz. Biol Chem. .

Abstract

Small RNAs govern almost every biological process in eukaryotes associating with the Argonaute (AGO) proteins to form the RNA-induced silencing complex (mRISC). AGO proteins constitute the core of RISCs with different members having variety of protein-binding partners and biochemical properties. This review focuses on the AGO subfamily of the AGOs that are ubiquitously expressed and are associated with small RNAs. The structure, function and role of the AGO proteins in the cell is discussed in detail.

Keywords: AGO; GW182; miRISC; miRNA.

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References

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