Infectious Scarring: Setting the Trigger for Intestinal Inflammation
- PMID: 29447693
- DOI: 10.1016/j.chom.2018.01.017
Infectious Scarring: Setting the Trigger for Intestinal Inflammation
Abstract
The initiating factors that trigger inflammatory bowel disease (IBD) are poorly understood. In a recent paper, Yang et al. (2017) demonstrate that IBD-like syndrome in mice can develop as a consequence of recurrent pathogen infection. Pathogenic triggering of inflammatory disease is a re-emerging concept that has significant therapeutic implications.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Recurrent infection progressively disables host protection against intestinal inflammation.Science. 2017 Dec 22;358(6370):eaao5610. doi: 10.1126/science.aao5610. Science. 2017. PMID: 29269445 Free PMC article.
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