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. 2018 Jun;91(2):144-146.
doi: 10.1016/j.diagmicrobio.2018.01.012. Epub 2018 Feb 2.

The Verigene dilemma: gram-negative polymicrobial bloodstream infections and clinical decision making

Kimberly C Claeys  1 , Emily L Heil  2 , Jason M Pogue  3 , Paul R Lephart  4 , J Kristie Johnson  5
Affiliations

The Verigene dilemma: gram-negative polymicrobial bloodstream infections and clinical decision making

Kimberly C Claeys et al. Diagn Microbiol Infect Dis. 2018 Jun.

Abstract

Verigene Blood-Culture Gram-Negative (GN) results in rapid identification of key GNs in bloodstream infections. Its use clinically is limited by low sensitivity in polymicrobial GN infections and concerns for inappropriate antibiotic modification. In a retrospective review of 1003 blood culture sets, the incidence of missed GNs was infrequent, <4%, with the potential to negatively impact the management of GN BSIs in <2% of cases.

Keywords: Bloodstream infection; Gram-negative; Microarray; Polymicrobial; Rapid diagnostics.

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