Experimental strategies for the study of cellular immunity in renal disease

Abstract

This overview has examined some of the current experimental options available for the study of cellular immunity in the immunopathogenesis of renal disease. T cell immunity, where it has been examined, seems to have a particularly pivotal role in orchestrating and regulating functional patterns of renal injury. The use of the research methods presented here for the study of cell-mediated interactional events in kidney disease, however, has lagged behind similar efforts in other organ systems. We hope, therefore, this report will serve to stimulate and strengthen further interest in the cell biology of the nephritogenic immune response.