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Case Reports
. 2017 Apr-Jun;61(2):137-143.
doi: 10.22336/rjo.2017.26.

Rare case of ocular tuberculosis in a diabetic patient: diagnostic and therapeutic dilemmas

Anca Pantalon  1 , Emanuela Găman  1 , Iustina-Silvia Crețu-Silivestru  1 , Ciprian Danielescu  1   2
Affiliations
Case Reports

Rare case of ocular tuberculosis in a diabetic patient: diagnostic and therapeutic dilemmas

Anca Pantalon et al. Rom J Ophthalmol. 2017 Apr-Jun.

Abstract

We present the case of a patient who was diagnosed by chance with macular hypopyon during a conventional interdisciplinary examination. The clinical context and the association of a systemic disease, such as uncontrolled type 1 diabetes, rendered further investigations in this patient. Due to his immunocompromised status, etiology such as ocular fungi, lymphomas, tuberculosis was taken into account. Thorough complex investigations oriented the diagnosis towards ocular tuberculosis involvement.

Keywords: Quantiferon; diabetes; ocular tuberculosis.

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Figures

Fig. 1
Fig. 1
OD - Anterior segment examination: mild conjunctival congestion with episcleral vessels dilation
Fig. 2
Fig. 2
OS - Anterior segment examination: normal
Fig. 3
Fig. 3
OD - Fundus examination (moderate non-proliferative diabetic retinopathy)
Fig. 4
Fig. 4
OD - Macular hypopyon
Fig. 5
Fig. 5
OS - Fundus examination (moderate non-proliferative diabetic retinopathy)
Fig. 6
Fig. 6
Macular hypopyon – stationary aspect at 6 months after presentation (no treatment was followed)
Fig. 7
Fig. 7
Thoracic X-ray: areas of non-homogenous condensation in both lungs, more prominent on the left side; bilateral hilar lymphadenopathy
Fig. 8
Fig. 8
Lung biopsy (HE coloring)
Fig. 9
Fig. 9
Lung biopsy (PAS coloring)
See this image and copyright information in PMC

References

    1. WHO Global tuberculosis control: key findings from the December 2009 WHO report. Wkly Epidemiol Rec. 2010;85(9):69–80. - PubMed
    1. Shakarchi FI. Ocular tuberculosis: current perspectives. Clin Ophthalmol. 2015;9:2223–2227. - PMC - PubMed
    1. Pereira-Silva JL, Marinho MMMA, Veloso TVB, Coelho Filho JC. Pulmonary Alveolar Proteinosis and tuberculosis in a diabetic patient: a rare or a seldom diagnosed association? Braz J Infect Dis. Aug. 2002;6(4) - PubMed
    1. Ang M, Chee SP. Controversies in ocular tuberculosis. Br J Ophthalmol. doi:10.1136/bjophthalmol-2016-309531. - PubMed
    1. Floros J, Lin HM, Garcia A, et al. Surfactant protein genetic marker alleles identify a subgroup of tuberculosis in a mexican population. J Infect Dis. 2000;182:1473–1478. - PubMed

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