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Editorial
. 2018 Dec;11(12):1834-1836.
doi: 10.1016/j.jcmg.2017.12.009. Epub 2018 Feb 14.

Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis

Joseph C Wu  1 , Xulei Qin  2 , Evgenios Neofytou  2
Affiliations
Editorial

Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis

Joseph C Wu et al. JACC Cardiovasc Imaging. 2018 Dec.
No abstract available

Keywords: duramycin; myocardial apoptosis; radionuclide imaging.

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Figures

Figure 1.
Figure 1.. Central pathways and imaging targets for apoptosis.
Both extrinsic pathway (cell-surface receptors) and intrinsic pathway (mitochondria) activate caspase-3 to finally result in apoptosis. The externalized phospholipid (i.e., PS and PE), activated caspase-3, and dissipated Δψm can be targeted by various radiotracers for noninvasive imaging of apoptosis. PS: phosphatidylserine; PE: phosphatidylethanolamine; Δψm: mitochondrial transmembrane potential.
See this image and copyright information in PMC

Comment on

References

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