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. 2017 Dec 31;8(2):668.
doi: 10.4081/jphia.2017.668.

A brief review on features of falciparum malaria during pregnancy

Alexandre Manirakiza  1 , Eugène Serdouma  2 , Richard Norbert Ngbalé  2 , Sandrine Moussa  1 , Samuel Gondjé  3 , Rock Mbetid Degana  3 , Gislain Géraud Banthas Bata  3 , Jean Methode Moyen  3 , Jean Delmont  4 , Gérard Grésenguet  2 , Abdoulaye Sepou  2
Affiliations

A brief review on features of falciparum malaria during pregnancy

Alexandre Manirakiza et al. J Public Health Afr. .

Abstract

Malaria in pregnancy is a serious public health problem in tropical areas. Frequently, the placenta is infected by accumulation of Plasmodium falciparum-infected erythrocytes in the intervillous space. Falciparum malaria acts during pregnancy by a range of mechanisms, and chronic or repeated infection and co-infections have insidious effects. The susceptibility of pregnant women to malaria is due to both immunological and humoral changes. Until a malaria vaccine becomes available, the deleterious effects of malaria in pregnancy can be avoided by protection against infection and prompt treatment with safe, effective antimalarial agents; however, concurrent infections such as with HIV and helminths during pregnancy are jeopardizing malaria control in sub-Saharan Africa.

Keywords: Malaria; Plasmodium falciparum; pregnancy.

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Conflict of interest statement

Conflict of interests: the authors have no conflict of interests.

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