Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Dec 31;8(2):668.
doi: 10.4081/jphia.2017.668.

A brief review on features of falciparum malaria during pregnancy

Alexandre Manirakiza  1 , Eugène Serdouma  2 , Richard Norbert Ngbalé  2 , Sandrine Moussa  1 , Samuel Gondjé  3 , Rock Mbetid Degana  3 , Gislain Géraud Banthas Bata  3 , Jean Methode Moyen  3 , Jean Delmont  4 , Gérard Grésenguet  2 , Abdoulaye Sepou  2
Affiliations

A brief review on features of falciparum malaria during pregnancy

Alexandre Manirakiza et al. J Public Health Afr. .

Abstract

Malaria in pregnancy is a serious public health problem in tropical areas. Frequently, the placenta is infected by accumulation of Plasmodium falciparum-infected erythrocytes in the intervillous space. Falciparum malaria acts during pregnancy by a range of mechanisms, and chronic or repeated infection and co-infections have insidious effects. The susceptibility of pregnant women to malaria is due to both immunological and humoral changes. Until a malaria vaccine becomes available, the deleterious effects of malaria in pregnancy can be avoided by protection against infection and prompt treatment with safe, effective antimalarial agents; however, concurrent infections such as with HIV and helminths during pregnancy are jeopardizing malaria control in sub-Saharan Africa.

Keywords: Malaria; Plasmodium falciparum; pregnancy.

PubMed Disclaimer

Conflict of interest statement

Conflict of interests: the authors have no conflict of interests.

Figures

Figure 1.
Figure 1.
Flow diagram of the numbers of articles reviewed.
See this image and copyright information in PMC

References

    1. WHO: World Malaria Report 2016. Geneva: World Health Organization; 2016.
    1. White NJ, Pukrittayakamee S, Hien TT, Faiz MA, Mokuolu OA, Dondorp AM: Malaria. Lancet 2014;383:723-35. - PubMed
    1. Parekh FK, Hernandez JN, Krogstad DJ, et al. Prevalence and risk of Plasmodium falciparum and P. vivax malaria among pregnant women living in the hypoendemic communities of the Peruvian Amazon. Am J Trop Med Hyg 2007;77:451-7. - PMC - PubMed
    1. Takem EN, D’Alessandro U. Malaria in pregnancy. Med J Hematol Infect Dis 2013;5:e2013010. - PMC - PubMed
    1. Desai M, ter Kuile FO, Nosten F, et al. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 2007;7: 93-104. - PubMed

LinkOut - more resources