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Case Reports
. 2017 Nov 16;4(1-4):18-23.
doi: 10.1159/000481727. eCollection 2017 Jan-Dec.

A 71-Year-Old Female with Myocardial Infarction and Long-Standing Ulcers on the Thigh

Eduardo De Flammineis  1 , Patrick M Mulvaney  2 , Stefan Kraft  3 , Martin C Mihm Jr  4 , Shinjita Das  5 , Daniela Kroshinsky  5
Affiliations
Case Reports

A 71-Year-Old Female with Myocardial Infarction and Long-Standing Ulcers on the Thigh

Eduardo De Flammineis et al. Dermatopathology (Basel). .

Abstract

Calciphylaxis is most commonly encountered in patients with end-stage renal disease; however, it is increasingly observed in nonuremic patients as well. It is important to consider and diagnose nonuremic calciphylaxis early, as prompt treatment and mitigation of associated risk factors is essential to improve long-term outcomes for these patients. Here, we present the case of a 71-year-old woman with atrial fibrillation on warfarin, but without renal disease, who presented with two long-standing ulcers on her thigh and was diagnosed with the aid of biopsy with calciphylaxis. We review the existing literature on the subject and offer this case as a representative report of a clinicopathologic correlation for this disorder.

Keywords: Calciphylaxis; Nonuremic calciphylaxis.

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Figures

Fig. 1.
Fig. 1.
Ulcers of the left anterior (a) and left medial (b) thigh with surrounding stellate erythema.
Fig. 2.
Fig. 2.
Calcium deposition in walls of subcutaneous vessels. a H&E. ×40. b H&E. ×100. c Von Kossa stain. ×400.
See this image and copyright information in PMC

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