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Review
. 2018 Mar;20(3):592-605.
doi: 10.1111/jch.13220. Epub 2018 Feb 19.

Subjective sleep quality, blood pressure, and hypertension: a meta-analysis

Kenneth Lo  1 , Brigitte Woo  2 , Martin Wong  3 , Wilson Tam  2
Affiliations
Review

Subjective sleep quality, blood pressure, and hypertension: a meta-analysis

Kenneth Lo et al. J Clin Hypertens (Greenwich). 2018 Mar.

Abstract

Sleep quality is an important aspect of sleep, but no meta-analysis has elucidated its relationship with blood pressure (BP) and hypertension. A meta-analysis was conducted in October 2016 using multiple databases, including Embase and Medline. Studies that assessed subjective sleep quality and BP or hypertension were included. Upon full-text evaluation, 29 articles from 45 041 patients were selected, of which 22 articles were included in the meta-analysis and seven were presented narratively. Poor sleep quality was significantly associated with a greater likelihood of hypertension (odds ratio, 1.48; P value = .01). Poor sleepers had higher average systolic BP (mean difference = 4.37, P value = .09) and diastolic BP (mean difference = 1.25, P value = .32) than normal sleepers without statistical significance. Patients with hypertension had significantly worse sleep quality scores (mean difference = 1.51, P value < .01), while BP dippers had significantly better scores (mean difference = -1.67, P value < .01). The findings highlight the relationship between sleep quality and hypertension.

Keywords: blood pressure; hypertension; meta-analysis; sleep quality.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Study selection
Figure 2
Figure 2
Forest plot for sleep quality and hypertension. CI indicates confidence interval; SD, standard deviation
Figure 3
Figure 3
Forest plot for sleep quality and systolic blood pressure. CI indicates confidence interval; SD, standard deviation
Figure 4
Figure 4
Forest plot for sleep quality and diastolic blood pressure. CI indicates confidence interval; SD, standard deviation
Figure 5
Figure 5
Forest plot for sleep quality scores between patients with and without hypertension. CI indicates confidence interval; SD, standard deviation
Figure 6
Figure 6
Forest plot for sleep quality scores between dippers and nondippers. CI indicates confidence interval; SD, standard deviation
See this image and copyright information in PMC

Comment in

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