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Review
. 2018 Feb:122:92-97.
doi: 10.1016/j.critrevonc.2017.12.017. Epub 2017 Dec 28.

The role of human papillomavirus vaccines in cervical cancer: Prevention and treatment

Giorgio Bogani  1 , Umberto Leone Roberti Maggiore  2 , Mauro Signorelli  2 , Fabio Martinelli  2 , Antonino Ditto  2 , Ilaria Sabatucci  2 , Lavinia Mosca  2 , Domenica Lorusso  2 , Francesco Raspagliesi  2
Affiliations
Review

The role of human papillomavirus vaccines in cervical cancer: Prevention and treatment

Giorgio Bogani et al. Crit Rev Oncol Hematol. 2018 Feb.

Abstract

Human papillomavirus (HPV) is the most common sexually transmitted disease, worldwide. Primary prevention thorough vaccination si able to reduce the burden of HPV-related lesions. Ten years ago the Food and drug Administration (FDA) approved the first vaccine against HPV. In the last decades, growing data on safety and effectiveness have been collected. In the present review we report the current knowledge on vaccine against HPV, highlighting the current value and prospective regarding the widespread diffusion of HPV vaccines. The role of emerging therapeutic vaccines is reviewed.

Keywords: Cervical cancer; HPV; Therapeutic vaccine; Vaccine.

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