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. 2018 May;45(5):287-293.
doi: 10.1097/OLQ.0000000000000754.

Prevalence of Rectal Chlamydial and Gonococcal Infections: A Systematic Review

Prevalence of Rectal Chlamydial and Gonococcal Infections: A Systematic Review

Courtney M Dewart et al. Sex Transm Dis. 2018 May.

Abstract

We undertook a systematic review to examine rectal Chlamydia trachomatis (Ct) and Neisseria gonorrhoeae (Ng) infections in women and men who have sex with men (MSM). English-language publications measuring rectal Ct or Ng prevalence using nucleic acid amplification tests were eligible. Searching multiple electronic databases, we identified 115 eligible reports published between January 2000 and November 2016. Overall, the prevalence of rectal Ct (9%) was higher than that of rectal Ng (4.7%). Rectal Ct prevalence was similar in MSM (9%) and women (9.2%), whereas rectal Ng prevalence was higher in MSM (6.1%) than in women (1.7%). Generally, rectal Ct prevalence was similar in sexually transmitted disease clinics (9.1%) and nonsexual health clinics (8.6%), whereas rectal Ng prevalence was somewhat lower in sexually transmitted disease clinics (4.5%) than in nonsexual health clinics (6%). These infections seem to be relatively common across a range of populations and clinical settings, highlighting the need for additional research on these preventable, treatable conditions.

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Conflict of interest statement

Conflict of Interest: All authors: None to report.

Figures

Figure 1.
Figure 1.
Flow of information through the different phases of the systematic review.
Figure 2.
Figure 2.
Rectal chlamydia prevalence by study site; dashed line depicts unweighted median prevalence (7.9%).
Figure 3.
Figure 3.
Rectal chlamydia prevalence among MSM; dashed line depicts unweighted median prevalence (7.9%). B, Rectal chlamydia prevalence among women; dashed line depicts unweighted median prevalence (7.1%).
Figure 4.
Figure 4.
Rectal gonorrhea prevalence by study site; dashed line depicts unweighted median prevalence (3.6%).
Figure 5.
Figure 5.
Rectal gonorrhea prevalence among MSM; dashed line depicts unweighted median prevalence (4.2%). B, Rectal gonorrhea prevalence among women; dashed line depicts unweighted median prevalence (1.2%).

References

    1. Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 2016. Atlanta: U.S. Department of Health and Human Services, 2017.
    1. Klausner J, Hook E. Current Diagnosis & Treatment of Sexually Transmitted Diseases. New York, NY: McGraw-Hill Companies, Inc, 2007.
    1. Chow EP, Cornelisse VJ, Read TR, et al. Saliva use as a lubricant for anal sex is a risk factor for rectal gonorrhoea among men who have sex with men, a new public health message: A cross-sectional survey. Sex Transm Infect 2016; 92:532–536. - PubMed
    1. Rank RG, Yeruva L. Hidden in plain sight: chlamydial gastrointestinal infection and its relevance to persistence in human genital infection. Infect Immun 2014; 82:1362–1371. - PMC - PubMed
    1. Yeruva L, Spencer N, Bowlin AK, et al. Chlamydial infection of the gastrointestinal tract: A reservoir for persistent infection. Pathog Dis 2013;68:88–95. - PMC - PubMed

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