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doi: 10.1016/j.immuni.2018.02.004.
T Cell LEGO: Identifying the Master Builders and What They Do
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- PMID: 29466746
- DOI: 10.1016/j.immuni.2018.02.004
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T Cell LEGO: Identifying the Master Builders and What They Do
Immunity.
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Free article
Abstract
Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.
Copyright © 2018 Elsevier Inc. All rights reserved.
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