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Review
. 2018 Feb 7:12:36.
doi: 10.3389/fnins.2018.00036. eCollection 2018.

Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda

Jennifer J Brout  1 , Miren Edelstein  1   2 , Mercede Erfanian  1   3 , Michael Mannino  4 , Lucy J Miller  1   5 , Romke Rouw  6 , Sukhbinder Kumar  1   7 , M Zachary Rosenthal  1   8   9
Affiliations
Review

Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda

Jennifer J Brout et al. Front Neurosci. .

Abstract

Misophonia is a neurobehavioral syndrome phenotypically characterized by heightened autonomic nervous system arousal and negative emotional reactivity (e. g., irritation, anger, anxiety) in response to a decreased tolerance for specific sounds. The aims of this review are to (a) characterize the current state of the field of research on misophonia, (b) highlight what can be inferred from the small research literature to inform treatment of individuals with misophonia, and (c) outline an agenda for research on this topic. We extend previous reviews on this topic by critically reviewing the research investigating mechanisms of misophonia and differences between misophonia and other conditions. In addition, we integrate this small but growing literature with basic and applied research from other literatures in a cross-disciplinary manner.

Keywords: defensive motivational systems; emotion regulation; fear circuitry; misophonia; sensory over-responsivity; sensory processing.

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